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Thbs2 gene

Web目的. 分析CD24基因在恶性胸膜间皮瘤(MPM)组织和细胞中的表达水平,探讨其与MPM患者临床病理特征及预后的关系。. 方法. 于2024年2月,利用UALCAN数据库分析下载的87例MPM患者CD24基因表达量与临床病理特征的关系。. 利用TIMER 2.0平台探讨MPM中CD24表达与肿瘤免疫 ... WebTHBS2 Gene, Drug Resistance, Tissue Distribution, Mutation Distribution, Variants, THBS2 Genome Browser, THBS2 References. THBS2 - Explore an overview of THBS2, with a histogram displaying coding mutations, full tabulated details of all associated variants, tissue distribution and any drug resistance data.

CD24基因在人恶性胸膜间皮瘤中的表达及其与预后的关系 - 中华劳 …

Web3 Feb 2024 · Thrombospondin-2 (THBS2) is a member of the matricellular calcium-binding glycoprotein family, which interacts with growth factors, cell receptors, and extracellular … WebTHBS2 (COSG69288) Genomic coordinates 6:169215780..169254044 (negative strand) Synonyms TSP2, CCDS34574.1, P35442, ENSG00000186340.14, NM_003247.3, … helm kerketuinen https://sportssai.com

7058 - Gene ResultTHBS2 thrombospondin 2 [ (human)]

Thrombospondin-2 is a protein that in humans is encoded by the THBS2 gene. The protein encoded by this gene belongs to the thrombospondin family. It is a disulfide-linked homotrimeric glycoprotein that mediates cell-to-cell and cell-to-matrix interactions. The role of the protein in cancer is controversial, contrasting studies show positive and negative roles for cancer development. Studies of th… Web9 Jan 2024 · Through binding to CD36, THBS2 regulates a diverse range of activities including angiogenesis, apoptosis and metastasis ( 13, 14 ). THBS2 is an FGF2 ligand that can block FGF2 interaction with proangiogenic receptors, such as heparin or FGFR1 ( 15 ). THBS2 Hep1 peptide can also bind actin to alter cytoskeletal reorganization ( 16 ). Web21 Mar 2024 · The protein encoded by this gene localizes to focal adhesions, regions of the plasma membrane where the cell attaches to the extracellular matrix. This protein crosslinks actin filaments and contains a Src homology 2 (SH2) domain, which is often found in molecules involved in signal transduction. This protein is a substrate of calpain II. helm kyt anak jalanan

[Expression of CD24 gene in human malignant pleural ... - PubMed

Category:Differential Expression Pattern of THBS1 and THBS2 in …

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Thbs2 gene

Prognostic and Immunological Role of THBS2 in Colorectal cancer …

Web8 Jan 2024 · CytoHubba selected the top ten hub genes, which included SPP1, TIMP1, SERPINE1, MMP3, COL1A1, BGN, THBS2, CDH2, CXCL8, and THY1. With the exception of SPP1, survival analysis using the Kaplan–Meier database showed that the levels of expression of these genes were associated with overall survival. WebAES Gene. AES. Name. amino-terminal enhancer of split. Description. The protein encoded by this gene is similar in sequence to the amino terminus of Drosophila enhancer of split groucho, a protein involved in neurogenesis during embryonic development. The encoded protein, which belongs to the groucho/TLE family of proteins, can function as a ...

Thbs2 gene

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Web16 Sep 2016 · Interestingly, combination the average of top 20 genes and THBS2 showed a higher risk in overall survival (p < 0.001, 2.890(1.676–4.981)) than the average of top 20 … Web3 Feb 2024 · THBS2 is Closely Related to the Poor Prognosis and Immune Cell Infiltration of Gastric Cancer Front Genet 2024 Feb 3;13:803460. doi: 10.3389/fgene.2024.803460. …

Web11 Apr 2024 · The gene expression data and the cell type labels of the head and neck cancer single-cell cohort used in the feature set validation was taken from the publication by Tirosh et al. (Gene Expression ... Webby Gene › THBS2 Antibodies; THBS2 Antibodies . Target Information. The Thrombospondin proteins (TSP 1-5) compose a family of glycoproteins that are involved in cell-to-cell and cell-to-matrix signaling. These extracellular, cell-surface proteins form complexes of both homo- and hetero-multimers. Thrombospondins play a role in development ...

Web15 Jun 2024 · Another example includes a loop surrounding the Thbs2 gene (Fig. 4g). Similar to Adcyap1 , the Thbs2 gene is also an anxiety-related gene 41 that has an oestrogen response element in the promoter ... Web1 Dec 2000 · Abstract Thrombospondin 2 (TSP2)-null mice, generated by targeted disruption of the Thbs2 gene, display a complex phenotype that is characterized, in part, by a variety of connective tissue abnormalities and increased vascular density in …

Web21 Mar 2024 · TNXB (Tenascin XB) is a Protein Coding gene. Diseases associated with TNXB include Ehlers-Danlos Syndrome, Classic-Like and Vesicoureteral Reflux 8 . Among its related pathways are PI3K-Akt signaling pathway and Extracellular matrix organization . Gene Ontology (GO) annotations related to this gene include heparin binding and collagen …

Web21 Aug 2024 · THBS2 binding and correlated genes were analyzed using String, GEPIA2, and TIMER 2.0. Results: Age and histological subtype were correlated with THBS2 level. High … helm kyt dj maru putihWebGene locations. mm10 chr17:14665500-14694262; mm9 chr17:14802507-14831269 helm kyt cross hijauWeb1 Jan 2006 · The THBS2 gene is 38,261 bases in size and is composed of 23 exons. Exons 3-22 encode the 5,808 base mRNA. Transcription. Unlike TSP1, TSP2 is less-to-moderately responsive to serum in mouse NIH3T3 and Swiss 3T3 cells respectively. Transcription of THBS2 in some human cancers is suppressed through hypermethylation. helm kyoto hitamWebTHBS2 GEO Profiles, NCBI Search the gene expression profiles from curated DataSets in the Gene Expression Omnibus (GEO) repository. Latest Publications: THBS2 (cancer-related) Chen X, Yang F, Zhang T, et al. MiR-9 promotes tumorigenesis and angiogenesis and is activated by MYC and OCT4 in human glioma. helm kyt kyoto aquamarineWeb10 Nov 2024 · Recent cancer studies have found that the thrombospondin (THBS) family, including THBS1, THBS2, THBS3, THBS4, and THBS5, play vital roles in the development and progression of human cancers. However, their relationships with tumor stage, prognosis, and tumor immunity in pan-cancer have not been systematically reported. In the present … helm kyt kyoto hitamWebThbs2-, Tsp-2-, TSP2-Gene: Thbs2 Location: Chr17:14885762-14914497 bp, - strand Genetic Position: Chr17, 8.95 cM, cytoband A3-B Alliance: Thbs2 tm1Bst page Thbs2 tm1Bst /Thbs2 tm1Bst mice show increased flexibility of tail tendons and ligaments such that a … helm kyt kyoto hitam glossyWebThbs2 Gene Detail Summary Symbol Thbs2 Name thrombospondin 2 Synonyms Thbs-2, Thrombospondin-2, TSP2 Feature Type protein coding gene IDs MGI:98738 NCBI Gene: … helm kyt kyoto putih visor venom