Trinucleotide repeat disorders, also known as microsatellite expansion diseases, are a set of over 50 genetic disorders caused by trinucleotide repeat expansion, a kind of mutation in which repeats of three nucleotides (trinucleotide repeats) increase in copy numbers until they cross a threshold above which they become unstable. Depending on its location, the unstable trinucleotide repeat may cause defects in a protein encoded by a gene; change the regulation of gene expression; pro… WebTAG members are identified, recruited, and selected as recognized independent experts in the Americas from the fields of public health, epidemiology, vaccinology, immunology, …
Strategic and Technical Advisory Group on Disease …
Tay-Sachs disease is a rare genetic disorder passed from parents to child. It's caused by the absence of an enzyme that helps break down fatty substances. These fatty substances, called gangliosides, build up to toxic levels in the brain and spinal cord and affect the function of the nerve cells. In the most … See more Tay-Sachs disease is a genetic disorder that is passed from parents to their children. It occurs when a child inherits a flaw (mutation) in the HEXA gene from … See more Because the gene change that causes Tay-Sachs disease is found more often in certain populations, risk factors for Tay-Sachs disease include having … See more WebMay 20, 2024 · Paget's disease of the breast starts on the nipple and extends to the dark circle of skin (areola) around the nipple. Paget's disease of the breast isn't related to … citation planete
Vaccine-preventable Diseases TAG - PAHO/WHO Pan …
WebJan 19, 2024 · In this article, learn about whether or not skin tags are cancerous. This article also covers causes of skin tags, how to recognize them, when to contact a doctor, … WebJan 27, 2024 · Skin tags are soft, noncancerous growths that usually form within the skin folds of the neck, armpits, breasts, groin area, and eyelids. These growths are loose collagen fibers that become lodged... WebJul 26, 2024 · Skin tags appear to be more common in: people who are overweight and obese those with diabetes women during pregnancy, possibly due to hormonal changes … citation plugin mendeley