WebSee the list of drugs that interact with Amlodipine. Includes information on severity of interaction and the level of evidence for it. ... Clarithromycin is predicted to increase the exposure to Amlodipine. Manufacturer advises monitor and adjust dose. ... Amlodipine causes a small increase in the exposure to Simvastatin. Manufacturer advises ... WebMay 3, 2011 · Concomitant administration of macrolides significantly increases plasma statin concentrations. 3 An increased risk of rhabdomyolysis has been reported when clarithromycin is combined with simvastatin. 4 5 Current guidance in the British National Formulary is to avoid concomitant administration of simvastatin and clarithromycin.
Rhabdomyolysis caused by interaction between rosuvastatin and ...
WebBoth Simvastatin and Clavulanate can increase the risk of hepatotoxicity. Cobicistat Cobicistat is predicted to increase the exposure to Simvastatin. Manufacturer advises … WebApr 10, 2024 · In addition, rhabdomyolysis has been reported to have occurred because of increased blood levels of statins due to drug interactions ... Bjerregaard Stage T, et al. Interaction potential between clarithromycin and individual statins-a systematic review. Basic Clin Pharmacol Toxicol. 2024;126:307–17. Article CAS PubMed Google Scholar lake pharma
Clarithromycin and simvastatin Interactions - Drugs.com
WebAbstract. Statins are commonly used in the treatment of hyperlipidaemia. Although the benefits of statins are well-documented, they have the potential to cause myopathy and rhabdomyolysis due to the complex interactions of drugs, comorbidities and genetics. The cytochrome P450 family consists of major enzymes involved in drug metabolism and ... WebJun 17, 2013 · Older people taking statins for high cholesterol should avoid taking the antibiotics clarithromycin or erythromycin at the same time because of potential kidney … WebJan 9, 2024 · The more common side effects of clarithromycin oral tablet can include: stomach pain diarrhea nausea vomiting abnormal taste in your mouth If these effects are mild, they may go away within a... jenis hosting