Scaffold attachment factor b2
WebSAFB2, also named as Scaffold attachment factor B2 or KIAA0138, is a 953 amino acid protein, which contains one SAP domain and one RRM (RNA recognition motif) domain. SAFB2 expressed at high levels in the CNS and at low levels in the liver. It also is expressed in a wide number of breast cancer cell lines. WebFeb 7, 2024 · Insight into the Structural Basis for Dual Nucleic Acid-Recognition by the Scaffold Attachment Factor B2 Protein Int J Mol Sci. 2024 Feb 7 ... The family of scaffold attachment factor B (SAFB) proteins comprises three members and was first identified as binders of the nuclear matrix/scaffold. Over the past two decades, SAFBs were shown to …
Scaffold attachment factor b2
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WebJun 23, 2024 · PDF Gynecologic cancers including cancers of the endometrium are a clinical problem (1-4). We mined published microarray data (5, 6) to discover genes... Find, read and cite all the research ... WebNov 26, 2024 · The location of a scaffold will make a big difference in whether or not it needs to be secured to a building. The type of ground the scaffolding rests on, the …
WebSep 1, 2015 · Scaffold attachment factor B2 (SAFB2) is a member of a protein family that also contains the paralog SAFB1 and a closely related protein scaffold attachment factor-like transcriptional modulator (SLTM). SAFB2 was originally identified as KIAA0138 and subsequently named SAFB2 based on its high homology to SAFB1 ... WebAug 31, 2011 · SCAFFOLD ATTACHMENT FACTOR B2; SAFB2 Alternative titles; symbols KIAA0138 HGNC Approved Gene Symbol: SAFB2 Cytogenetic location: 19p13.3 Genomic …
Webits 70% homologous paralogue, scaffold attachment factor B2 (SAFB2). ERH interacts directly in the nucleus with the C-terminal Arg-Gly-rich region of SAFB1/2 and co-localizes with it in the insoluble nuclear frac-tion. ERH, a small ubiquitous protein with striking homology among spe-cies and a unique structure, has also been implicated in ... WebThe scaffold attachment factor SAFB2, a component of high molecular weight nuclear protein complexes which contains a core set of protein interaction partners, functions as an estrogen receptor corepressor. It directly interacts with ER alpha repressing transcription via repression domains. Its overexpression results in inhibition of proliferation.
WebFeb 15, 2024 · Scaffold attachment factor B Annotation Symbol CG6995 Feature Type protein_coding_gene FlyBase ID FBgn0039229 Gene Model Status Current Stock Availability 5 publicly available Gene Summary Contribute a Gene Snapshot for this gene. All Summaries Also Known As SAFB Key Links Genomic Location Cytogenetic map 96A23-96A23 …
WebScaffold attachment factor B2 is a protein that in humans is encoded by the SAFB2 gene. [5] [6] Interactions [ edit] SAFB2 has been shown to interact with Estrogen receptor alpha [5] and SAFB. [5] References [ edit] ^ a b c GRCh38: Ensembl release 89: ENSG00000130254 - Ensembl, May 2024 otc drugs for urinary tract infectionWebJun 18, 2015 · SAFB1 (scaffold attachment factor B1) and a second family member SAFB2, are multifunctional proteins implicated in a variety of cellular processes including cell … rocketbook instructionsWebThe family of scaffold attachment factor B (SAFB) proteins comprises three members and was first identified as binders of the nuclear matrix/scaffold. Over the past two decades, SAFBs were shown to act in DNA repair, mRNA/(l)ncRNA processing and as part of protein complexes with chromatin-modifying enzymes. rocketbook index cardsWebscaffold attachment factor B2 GeneRIFs: Gene References Into Functions SAFB2 Enables the Processing of Suboptimal Stem-Loop Structures in Clustered Primary miRNA … rocketbook in the classroomWebMar 21, 2024 · SAFB2 (Scaffold Attachment Factor B2) is a Protein Coding gene. Diseases associated with SAFB2 include Breast Cancer. Gene Ontology (GO) annotations related to … rocketbook infinity notebookWebIt is Scaffold Attachment Factor B2. Scaffold Attachment Factor B2 listed as SAFB2 Scaffold Attachment Factor B2 - How is Scaffold Attachment Factor B2 abbreviated? rocketbook - infinity notebookWebJan 18, 2024 · Scaffold attachment factor-B2 (SAFB2) is identified as a nuclear matrix-associated protein and belongs to the family of nuclear proteins [ 4 ]. The SAFB2 gene maps to human chromosome 19p13.3, which localized in the nuclear matrix and has a broad expression profile in human tissues [ 5 ]. rocketbook in stores